^（134）Cs在大鼠整体、骨骼和睾丸中转运滞留及剂量估算

TRANSFERENCE, RETENTION AS WELL AS DOSE-ESTIMATION OF ￣(134)Cs IN THE RAT'S WHOLE BODY, SKELETON AND TESTES

研究了裂片１３４Ｃｓ内污染时在整体水平、骨骼和睾丸的转运、滞留，及其相应的吸收剂量估算。用整体测量装置探讨１３４Ｃｓ在整体的滞留，拟合的滞留方程为：Ｒ（ｔ）＝１８．０４ｅ－９．３１７５ｔ＋４５．１３ｅ－０．０４２３ｔ在整体滞留过程中包括两个滞留半减期，其中快组分Ｔ１＝０．０７ｄ，而慢组分Ｔ２＝１６．３８ｄ。并估算了其吸收剂量．根据１３４Ｃｓ在骨骼和睾丸中７周内的转运和滞留动态变化，拟合了１３４Ｃｓ在骨组织的滞留方程为：Ｒ（ｔ）＝０．００２９ｅ－０．１２１ｔ，观察到在骨中的滞留半减期只有５．７３ｄ。而拟合的１３４Ｃｓ在睾丸中的滞留方程为：Ｒ（ｔ）＝０．００４７ｅ－０．１３３ｔ，即在睾丸中的滞留半减期亦只有５．２１ｄ．可见随着１３４Ｃｓ内污染后时间的延长，其在骨骼和睾丸中的滞留均可迅速下降，而其吸收剂量呈缓慢增长。

In this paper the whole body transference and retention dynamics of134Cs by whole body counter were well described by a two--exponential function, that is= R(t) = 18. 04 e-9.3157t + 45. 13 e--0.0473t. There are two retention .components, fast and slow. The effective and biological T1/2 were 0. 07 and 16.38 days respectively.Results indicated that after i. v. injection radionuclides 134Cs through 7 weeksObservation,the retention data in skeleton could be fit well by an exponential expression: R(t;) = 0.0029 e-o.121t. Where the retention T1/2 was only 5 .73 d. While theretention data of 134Cs in testes also could be well described by an exponential equation: R(t) = 0. 0047 e-0. 133t. Where the retention T1/2 was also only 5. 21 d. As awhole, the study showed that the dynamic retention of radioactivities of 134Cs inthe whole body, skeleton and testes fall rapidly with the prolongation of observingtime. So that the absorption dose in the whole body, skeleton and testes roseslowly.