4－氧代戊酸酯类缩酮的脱保护作用

SYNTHESIS OF KETALS OF 4─OXOPENTANATE。CONVERSION OF KETALS OF 4─OXOPENTANATE TO 4─OXOPENTANTE PROMOTED BY ZrCl_4─NaBH_4

糠醛经康尼查罗反应、开环，缩合制得４──氧化戊酸酯及缩酮。后者能在ＺｒＣｌ＿４／ＮａＢＨ＿４作用下于３０℃、乙醚溶液中高产率地脱保护再生为４──氧代戊酸酯。

Ketals of 4─oxopentanate have been synthesized from furfural by Cannizaro reaction fol-lowed by ring opening and condensation. These ketals can be deprotected by using ZrCl_4─NaBH_4in Et_2O at 30℃ in high yield.