四个香豆素磺酰氯衍生物的合成及其荧光性能的研究

Synthesis and Study of Fluorogenic Property Four Kinds of Coumarin Sulphonyl Chloride Derivatives

四个香豆素磺酰氯衍生物的合成及其荧光性能的研究曹秋娥，徐其亨（云南大学化学系，昆明，６５００９１）关键词香豆素磺酰氯衍生物，荧光试剂，荧光性能香豆素衍生物是一类较好的荧光试剂，本文以香豆素为母体，合成了４个香豆素磺酰氯衍生物：４－甲基－７－羟基香豆素...

Four kinds of coumarin sulphonyl chloride derivatives were synthesized and identified in this article. They are 4-methyl umbelliferone-6-sulphonyl chloride (MUS-Cl),4-methyl-7-acetoxyl coumarin-6-sulphonyl chloride (MACS-Cl),4-methyl-7-methyoxyl coumarin-6-sulphonyl chloride (MMCS-Cl),4-methyl coumarin-6-sulphonyl chloride (MCSCl).The effects of fluorogenic property of these reagents by the solvent polarity, pH of solution, time of light shining, effects of the surfactant were studied. Throught separation of reaction mixture by TLC, we also have studied the reaction of these reagents with aminoacid or amine and the possibility of these reagents as fluorogenic probe for these compounds.The results have suggested that all these reagents may be used as fluorogenic probe for amino-acid and amine.