九子参中新的三萜皂甙──九子参甙

Rubicunoside A──a New Acetylated Triterpenoid Saponin from Silene Rubicunda

九子参中新的三萜皂甙──九子参甙谭宁华，赵守训，周俊，陈昌祥，王德祖，何以能（中国药科大学植物化学研究室，南京）（中国科学院昆明植物研究所植物化学开放实验室，昆明，６５０２０４）关键词九子参，石竹科，三萜皂甙，九子参甙Ａ，甘草酸酶九子参（Ｓｉｌｅｎｅ...

A new acetylated triterpenoid saponin,rubicunoside A(1),was isolated from the roots of Silene rubicunda.On the basis of extensive chemical,enzymic,and spectral methods the structure was elucidated as 3-O-β-D-galactopyranosyl-(1-2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl quillaic acid 28-O-β-D-xylopyranosyl-(1-3)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→3)-[2'-OAc]-β-D-fucopyranosyl-(1-2)-[3'-OAc]-β-D-fucopyranoside(1).The enzymic cleavage method with glyrrhizinic acid hydrolase providing selectively 3-oligosaccharides and 28-O-glucosides,and partial methanolysis providing selectively 28-oligosaccharides from 3,28-O-bisglucosides were effective for the structure elucidation.