摘要
报道了新型N-异丙基-O-芳基O'-半乳吡喃糖基硫代磷酰胺酯的合成,并对有关反应进行了讨论.通过重结晶分离得到了化合物N-异丙基-O-(对-氯苯基)-O'-半乳吡喃糖基硫代磷酰胺酯的纯异构体,单晶X射线衍射分析结果表明,此纯异构体分子中手性磷原子的构型为R。初步测定了这类化合物的除草活性及抗病活性。
The synthesis of novel N-isopropyl-O-aryl-O'-galactopyranosyl thiophosphoramidates was reported,and the conditions of the reactions were discussed.A pure isomer of N-isopropyl-O-(p-chlorophenyl)-O'-galactopyranosyl thiophosphoramidate 3_d,3d' , was obtained by recrystallization from diethyl ether-petroleum ether. The result of X-ray diffraction analysis showed that the configuration of the chiral phosphorus atom of 3_d' was of R-form.The herbicidal and antidisease activities of the title compounds were tested.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1994年第11期1643-1646,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
南开大学元素有机化学国家重点实验室基金
关键词
硫代磷酰胺酯
结构
合成
生物活性
Thiophosphoramidate,Galactopyranosyl, Herbicidal activity, Antidisease activity