微波干法催化芳香醛与绕丹宁及N－苯基绕丹宁的缩合反应

The Condensation of Rhodanine or N-Phenylrhodanine with Aromatic Aldehyde Under Microwave,Solid Base as a Supporter

利用微波辐射和固体碱性载体试剂催化绕丹宁及Ｎ－苯基绕丹宁和芳香醛的缩合反应合成了１４个绕丹宁衍生物并研究了影响反应的因素。

The condensation reaction of rhodanine or N-phenylrhodanine with aromatic aldehyde was catalyzed by microwave irradiation and with solid base as a supporter. The effects of basic supporter, microwave power and time on the reaction were investigated. Compared with conventional method without solvent or microwave. this method has better the advantage in yields, shorter reaction time and milder reaction conditions. Using 450 W microwave and K_2CO_3/Al_2O3 as basic supporter makes the condensation reaction speed above 10￣2 time faster.Fourteen rhodanine derivatives are obtained.