广西鼻咽癌预防研究（综述）

Preventive Study for NasopharyngealCarcinoma in Guangxi (Summarg)

总结鼻咽癌血清学诊断方法在广酉鼻咽癌Ⅱ级预防中的应用及推广成果；综述鼻咽癌发生的可能原因和预防研究的进展，如：中草药、土壤和食物激活ＥＢ病毒抗原的实验研究，微量元素与鼻咽癌的关系研究，人鼻咽癌裸鼠移植瘤株的建立，核仁组成区的嗜银蛋白（ＡｇＮＯＲ）检测、血清中β－微球蛋白检测，浓度梯度聚丙烯凝胶电泳检测患者血清和癌组织中ＬＤＨ同工酶以及鼻咽癌组织抽出液的纤溶酶原激活物活性测定。认为，对查出ＶＣＡ－ＩｇＡ抗体阳性者应视为鼻咽癌风险高危人群，并进行追踪观察，同时配合三级防癌网建设，强化人群对早期癌信号的认识，是目前行之有效的鼻咽癌Ⅱ级预防方法和途径。

The application and extension of the serologicol diagnosis method in the Ⅱ rank preventionof nasopharyngeal carcinoma (NPC) are summarized. The possible factors that cause NPC and the development of the diagnosis studies on NPC are also summarized, such as the experimental study of Chinese medicine herb,soil and food activating EBV, the study of relation between trace element and NPC,the study of primary carcinoma in nasopharynx and metastatic carcinoma in liver inoculated to nudemice, the investigation of the argyrophil protein in nucleolus area, β2-microglobulin in sera, LDH Isoenzyme in sera and nasopharynx tissue and the detection of plasminogen activator with fibre protein plate.Surveying the masses who are checked out with VCA-IgA positive and should be regarded as the highrisk people with NPC, meanwhile combinating the building of the Ⅲ rank anti-cancer net and strengthening the attention of people to the signal of early stage NPC would be effective measures in the NPCⅡ rank prevention at the monment.