必须对重性精神病实施已知遗传病的检查

Examination of Known Hereditary Disease for Serious Cases of Psychosis

本文剖析四个家庭，均有２～３个一级亲属被精神病院确诊为重性精神病患者。经检查，实质是轻型地中海贫血和／或肝炎、Ｇ６ＰＤ缺乏、脆性Ｘ染色体患者出现的精神症状。揭示重性精神病的家族现象实质可能是己知遗传病或传染病出现的家族性精神症状．而不存在至今未明的原发精神病基因。分析精神症状产生的机理实质是脑的内环境稳态的破坏。希望要对精神病患者进行己知遗传病的检查，从而根据原发遗传病实行优生优育措施，并对精神病患者实施对因治疗。

The diagnosis of serious psychosis in 9 patients of 4 famllies was confirmedby psychiatric hospitals. Later they were found to hdtve mental symptomsCaused by glucose 6-phosp hate dehydrogenase (G6PD) deficiency,thalassemiaand/or hepatitis,or fragile X-chromosome syndrome. It was shown thatfamilial serious psychosis may manifest with mental symptoms caused byknown hereditery diseases or infectious diseases but not by unknown psychosisgenes. The mental symptoms may be caused by the breaking down of cerebralhomeostasis. It is suggested that examination of known hereditary diseaseshould be carried out for the psychiatric patients, so that eugenic measuresand causative treatment can be empbyed properly.