血清唾液酸的测定在良恶性病变中的诊断价值

Diagnostic Value of Determination of Serum Sialic Acid for Benign and Malignant Lesions

作者测定了４８例肝癌、６０例其它癌症及４５例肝硬化、５２例胃十二指肠良性溃疡患者血清唾液酸（ＳＡ）水平。结果表明，恶性病变患者ＳＡ明显高于正常对照组及其它良性疾病组。肝癌及其它癌症ＳＡ的阳性率分别为９２％和８４％，并明显高于肝硬化与胃十二指肠溃疡，本文提示血清ＳＡ测定在良恶性病变的鉴别诊断上有一定价值。

Serum sialic acid(SA)was determined in 48 patients with hepatocellular carcinoma,60 with other cancers,45 with cirrhosis and, 52 with gastroduodenal benign ulceration and in 50 normal controls,The results showed that SA level was significantly higher in patients with malignant lesions than that in the normal controls, and that there was no significant difference of SA level between benign lesion groups and normal controls.In patients with hepatic carcinoma and other malignant tumor, SA positive rate was 92%, and 84%respectively,that were significantly higher than that for both cirrhosis and gastroduodenal benign ulcer. The results indicated that serum SA level may be a useful index for the differential diagnosis between benign and malignant lesions.