4Jacques PF. Relation between folate status, a common mutation in methylene tetrahydrofolate ruductase, and plasma homocysteine eoneentrations[ J ]. Circulation, 1996, 93(1):7-9.
5Zintzaras E, Chatzoulis DZ, Karabatsas CH, et al. The relationship between C667T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis [J]. J Hun Genet, 2005, 50(6):267-275.
6Moyers S, Bailey LB. Fetal malformations and folate metabolism: review of recent evidence[ J ]. Nutri Rev, 2001, 59(7):215-224.
7Stamler JS, Osbome JA , Jaraki O, et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen [ J ]. J Clin Invest, 1993, 91 (1):308-318.
8Tsai JC, Wang H, Perrella MA, et al. Induction of cyclin A gene expression by homocysteine in vascular smooth muscle ceils [J]. J Clin Invest, 1996, 97(1):146-153.
9Matschinsky FM.Glucokinase as glucose sensor and metabolie signal generator in pancreatie B cells and hepatolytes. Diabetes . 1990
10paul R J,et al. American Journal of Physiology . 1983
