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5α-还原酶抑制剂Finasteride 被引量:1

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作者 周瑞海
出处 《国外医药(合成药.生化药.制剂分册)》 1994年第1期23-26,共4页 World Pharmacy
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  • 1郑锦鸿,徐芳,廖清江.非那甾胺合成过程中两个5β异构体的分离和鉴定[J].中国药科大学学报,1996,27(3):129-130. 被引量:8
  • 2郑锦鸿,徐芳,廖清江.良性前列腺增生治疗新药非那甾胺的合成[J].中国药物化学杂志,1996,6(3):203-206. 被引量:22
  • 3XIANG-SHU FEI, WEI-SHENG TIAN, QING-YUN CHEN. Synthesis of 4-tdfluoromethylsteroids: A novel class of steroid 5a-reductase inhibitors [J]. Bioorganic & Medicinal Chemistry Letters, 1997, 7(24): 3113-3118.
  • 4XUN LI, SHANKAR M S, VAN LUU-THE, JEAN COTE. Vinyl fluoride as a mimic of the ‘intermediate'enol form in the 5α-reductase transformation: synthesis and in vitro activity of (N-1',1'-dimethylethyl)-3-haloandrost-3,5-diene-17β-carboxamides [J]. Bioorganic & Medicinal Chemistry, 1996, 4(1): 55-60.
  • 5RASMUSSON G H, REYNOLDS G F, UTNE T, et al. Azasteroids as inhibitors of rat prostatic 5α-reductase[J]. J Med Chem, 1984, 27: 1690-1695.
  • 6RASMUSSON G H, REYNOLDS G F, STEINBERG N G, et al. Azasteroides: structure-activity relationship for inhibition of 5α-reductase and androgen receptor binding [J]. J Med Chem, 1986, 29: 2298-2313.
  • 7RASMUSSON G H. 17 Beta-subatituted-4-aza-androstenone and their use as 5alpha-reductase inhibitors: EP,155096[P]. 1985-09-18.
  • 8RASMISSON G H, REYNOLDS G F. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors: US, 4760071 [P]. 1988.
  • 9GUARNA A, DANZA G. Synthesis of 5,6,6-[^2H3]finasteride and quantitative determination of finasteride in human plasma at picogram level by an isotope-dilution mass spectrometric method [J]. Journal of Chromatography B, 1995, 674: 197-204.
  • 10GARY H RASMUSSON, GLENN F REYNOLDS, NATHAN G STEINBERG Azasteroids: structure-aclivity relationships for inhibition of 5α-reductase and of androgen receptor binding [J]. J Med Chem, 1986, 29:2298-2315.

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