摘要
用放射免疫法测定了16名健康飞行员急性低压缺氧前后的血清内源性类洋地黄物质(EDLS)含量,并以16名健康地面人员作对照.结果发现,缺氧前两组含量无明显差异(P>0.05),说明飞行因素对EDLS的释放无重要影响.急性低压缺氧后,血清中EDLS含量明显增高,与对照组比,差异显著(P<O.01).提示急性中度缺氧也能引起体内EDLS分泌增加.但和Ⅰ期高血压病以及Ⅱ级心功能不全患者比较,其EDLS增加的幅度远远低于后两种情况,说明急性中度缺氧时,血清中EDLS含量的增加,可能是一种保护性的应激反应,对飞行人员不构成重要损害.
The content of serum endogenous digitalis-like substance (EDLS)was measured by radioimmunosssay in 16 healthy male pilots before and after acute hypoxia and 16 healthy male ground personnel weretaken as a control gronp. The results showed that the contents of serum EDLS in the two groups were not significantly different before acute hypoxia(p>0.05). This suggested that the effect of the flying factors on the secretion of EDLS was not obvious. The increase of serum EDLS after acute hypoxia was significant. There wassignificant difference compared with the control group(p<0.01). This showed that acute moderate hypoxia canalso cause the increase of secretion of serum EDLS in the body. But the increase of EDLS content was muthlower than the patients with hypertension I phase and mild heart failure. This suggested that the increase ofserum EDLS content after acute moderate hypoxia could be a protective stress. It alao showed that there was not obvious damage to the pilots.
