2－（三氯甲基）－2－丙醇的相转移催化法合成研究

Phase Transfer Catalyzed Synthesis of 2-(Trichloromethyl)-2-propanol

用聚乙二醇－４００作为相转移催化剂合成２－（三氯甲基）－２－丙醇，反应在碱性介质中进行，条件温和，反应温度控制在５～１０℃原料的摩尔配比为丙酮：氯仿：氢氧化钠：聚乙二醇－４００＝１０：１０：７：１．产率为３０．４％。

This paper reports the phase transfer catalyzed synthesis of 2-(trichloromethyl)-2-propanol using polyethylene glycol-400 as a phase transfer catalyst.Its reaction condition ismild,and the reaction carries out between acetone and chlorobrm in alkaline medium.The rawmeterial mol ratio is acetone:chloroform:sodium hydrate:catalyst=10:10:7:1.By usingthis method,a vield of 30.4%could be obtained.