聚合酶链反应诊断男性淋菌性尿道炎

Diagnosis of Male N Gonorrhoeae Urethritisby Polymerase Chain Reaction

用淋球菌聚合酶链反应诊断男性淋菌性尿道炎，６１例患者中９例作分泌物培养和ＰＣＲ，培养阳性２例，ＰＣＲ阳性５例；５２例先取尿道拭子作培养，后取始段晨尿作ＰＣＲ，培养阳性１例，ＰＣＲ阳性１８例．培养总阳性率４．９２％，ＰＣＲ总阳性率３７．８％，两者有显著性差异．笔者认为晨尿淋菌ＰＣＲ可作为一种敏感方法用于本病的诊断．

The article has reported 61 cases of male N gonorrhoeae uretritis diagnosed by poly-merase chain rcaction (PCR). In 9 cases accepting both culture and PCR with secrction, the posi-tive cases are 2 and 5 respectively. In 52 cases accepting culture with urethral swab and PCR withthe first morning urine, the positive cases are 1 and 18 respectively. The significant difference hasbeen found between PCR (37. 8% , 5 + 18/61 ) and culture (4. 92%, 2 + 1/61) . The resultshows that PCR is a sensitive method of diagnosing N gonorrhoeae urethritis.