含镁极化液防治肺心病快速心律失常的研究

Prevention and treatment of tachy-arrhythmia with magnesium polarized liquid in cor-pulmonale

对７４例肺心病患者的血镁（ＳＭｇ）含量、ＳＭｇ与快速心律失常（ＴＡ）的关系以及含镁极化液（ＧＩＫＭｇ）防治ＴＡ的疗效进行观察。结果显示：７４例肺心病患者治疗前、后有低Ｍｇ血症者４５例（６０．８％）；低Ｍｇ组各种ＴＡ发病率明显高于ＳＭｇ正常组。将入院时有ＴＡ的４８例分为ＧＩＫＭｇ组２６例和对照组２２例，ＧＩＫＭｇ治疗总有效率（９０．０％）高于对照组（５１．１％），Ｐ＜０．０１；对低ＳＭｇ的ＴＡ疗效（９４．３％）略优于正常ＳＭｇ（８０．０％），Ｐ＞０．０５。无ＴＡ的２６例分为ＧＩＫＭｇ预防组１２例和对照组１４例，预防用ＧＩＫＭｇ组ＴＡ发病率（２５．０％）明显低于对照组（６４．３％），Ｐ＜０．０１。提示：肺心病ＴＡ的发生与低Ｍｇ有关，用Ｍｇ预防治疗效果良好。

The contents of serum magnesium(SMg) in 74 patients with cor-pulmonale,the relation between SMg and tachyarrhythmias(TA) and the prevention and treatment of TA with magnesium polarized liquid(GIKMg) were studied.The results showed:1.the overall incidence of hypomagnesemia was 60.8%(45 out of 74 patients),2.the incidence of TA increased significantly in patients with hypomagnesemia as compared with that of the normal SMG(P<0.01),3.the total clinical effect of the GIKMg group was significantly increased in patients with TA in comparison with the controls(90.0%and 51.1% respectively,P<0.05),4.the total clinical effect of the hypomagnesemia group(94.3%)was slightly greater than that of the normal SMg group(80.0%),but there was no significant difference(P>0.05) between the two groups,and 5.TA incidence decreased significantly in patients with GIKMg group in comparison with the controls(25.0%and 64.3%respectively,P(0.01).Our results suggest that TA in patients with cor-pulmonale may be related to hypomagnesemia. The prevention and treatment of TA with magnesium was satisfactory.