软骨母细胞瘤临床分析（附12例报告）

Clinical Analysis of Chandroblastoma(A Report of 12 Cases)

本文报告１２例软骨母细胞瘤。该病临床上少见，多为良性，偶有恶性，好发于四肢骨骨骺。多发生在２０岁左右的青年，男性多于女性。临床症状轻，如发生在关节附近可引起关节肿胀，活动受限。典型Ｘ线征象是好发于干骺尚未融合的骨骺部，常是偏心型，有钙化，边缘里硬化的囊性透亮区。本病的病理特点是大体病理肿瘤组织为灰白色的肉芽组织，可见砂粒样钙化物，看不到成熟的软骨。显微镜下肿瘤成份主要是成软骨细胞。治疗方法主要是手术刮除加植骨，以植入自体骨最佳。

This article reports 12 cases of chondroblastoma,which is seldom seen in clinical practice,and in most cases is benign,occasionally malignant. It occurs mostly in the epiphysis ofthe bones of limbs,and mostly in the youth of about 20,more males than females. The clinicalsymptoms are light. Orthroncus may be caused if they occur near the joint and the activity ofthe joint is limited. The typical X-ray syndrome shows that it mostly occurs in the osteoepiphyseal portion where the epiphysis has not been fused,often appears decentered and calcificwith the edges presenting a sclerotic,cystic and transparent area. The pathological characteristics are as follows:pathologic tumor tissues are approximately greyish granulation tissues;arenoid calcification can be seen;mature cartilage can not been seen; under a microscope,tumor components are mainly shondroplasts. The major treatment is curettage and bone grafting.The self bone grafting is the best.