过氧化氢──戊二醛复合消毒液稳定性与杀菌效果的初步研究

Study on the Stability and the Bactericidal Efficacy of Hydrogen Peroxide-Glutaraldehyde Compound Solution

本文报告用聚氧乙烯脂肪醇醚作稳定剂研制过氧化氢－戊二醛复合消毒液，并在室温不避光保存条件下对其稳定性及存放６个月后的杀菌效果进行了观测。结果表明，在室温下，该复合消毒液放置于密闭玻璃瓶中在放１８０天后，过氧化氢有效浓度由３％下降到２．８５％，下降率为４．７７％；戊二醛有效浓度由０．５％下降到０．４５７％，下降率为８．６％。此时，该消毒液对金黄色葡萄球菌、大肠杆菌和枯草杆菌黑色变种芽胞仍具有很强的杀灭能力，其杀灭效果与即时配制的２％中性戊二醛相同。

A compound disinfectant was prepared by addition of 1% polyoxyhylene alcohol acted as a stabilizer into 3%Hydrogen Peroxide and 0.5%Glutaraldehyde Solution.The stability and the efficacy of the disinfectant in killing bacteria was studied in laboratory.The results indicated that decrease rate of hydrogen peroxide content was 4.77%and decrease rate of glutaraldehyde content was 8.6%after storage for l80 days at room temperature (6℃～30℃).The solution could still maintain excellent killing effect on bacteria and it could kill completely staphyloccus aureus(ATCC-6538) and Escherichia coli(ATCC-8099) in l min,and kill completely B subtilis var niger spore(ATCC-9372) in 60 min.