生物活性骨水泥的实验研究

An Experimental Study of Bioactive Bone Cement

本文介绍生物活性骨水泥α－Ｃａ，（ＰＯ４）２（简称α－ＴＣＰ）的制备过程，ＮＨ４Ｈ２ＰＯ４是生物活性骨水泥的最好促凝剂，加入羟基磷灰石粉末和提高ＮＨ４Ｈ２ＰＯ４浓度可加快α－ＴＣＰ水化硬化过程。作者测α－ＴＣＰ具有较强的抗压、抗折强度。动物实验表明，α－ＴＣＰ具有良好的生物相容性，生物活性和骨诱导能力，可用于充填骨腔和固定人工关节。

This article presents the preparing procedure of the bioactive bone cement. NH4H2PO4 is the best set acclerator to α-Ca3(PO4)2(NH4)H2PO4 bone cement. The hydration and hardening of α-Ca3(PO4)2. The physical feature of the bone cement was testified. It showed that the bone cement had better compressive and blending strength. An animal experiment demonstrated that the bioactive bone cement bad good biocompatibility, bioacivity and osteconductive potential and could be used to fill up the bone cavity as well as fix artificila joint.