摘要
采用酶免疫法检测104例慢性肝病和164例献血员丙型肝炎抗体(抗-HCV),阳性率分别为18.3%(19/104)、1.8%(3/164);慢性肝病中HBV/HCV双重感染13例。HBV/HCV双重感染组(B组)与单纯丙型肝炎组(A组)谷丙转氨酶(ALT)差异无显著性(P>0.05)。与单纯慢性乙型肝炎组(C组)ALT差异有显著性(P<0.05);3组间血清总胆红素差异有显著性(P<0.05)。本文结果表明:HBV/HCV双重感染可加重肝脏损害,多数病例未见HBV与HCV干扰现象;正常人群也存在丙型肝炎隐性感染。
Anti-HCV was determined in the sera of 104 cases of chronic hepatitis and 164 blood doners by EIA diagnostic system. The positive rate was 18.3%(19/104)and 1.8%(3/164) respectively, among the 19 cases ,13 cases were HBV/HCV double infection. The difference of average level of total bilirubin was statistically significant(P<0.05) among the group B with HBV/HCV double infection, the group A with chronic hepatitis of single HCV infection and the group C with chronic hepatitis of single HBV infection. The difference of average level of ALT were statistically significant(P<0.05)between the group B and the group C, but not statistically significant between the group B and the group A. These results indicate that HBV/HCV double infection may accelerate the damage of liver tissue, there wasn't evidence of interference of replication of HBV by HCV infection.
关键词
乙型肝炎
流行病学
肝疾病
丙型肝炎
血清学
hepatitis B/EP
hepatitis, viral, non-A, non-B/EP
liver diseases