3－乙酰基酚酮还原新途径的研究

Research on new reduction route of 3-acetyltropolone

探讨了从３－乙酰基酚酮出发经甲胺基化、还原、水解合成了３－（２－羟乙基）酚酮的新合成路线，使总收率从原来的２０．５％提高到５９．２％。所合成的化合物３为尚未见文献报道的新化合物。其结构已经红外光谱、核磁共振谱及元素分析征实．

In this paper,we studied a new route of synthesis of 3-acetyltropolone by methylamination of 3-acetyltropolone, reductipn and hydrolysis. The totalyield was 59 .2%. The structure of the new synthesized compound 3 was confirmed by elemental analysis,IR and 1HNMR spectroscopy.