利用微生物检测环境有机化合物的致突变性

THE MUTAGENICITY DETECTION OF ORGANIC COMPOUNDS IN THE ENVIRONMENT USING MICROORGANISMS

运用微生物检测致突变性的方法有很多种,一般都是简便,快速,灵敏,并且样品用量较少,非常适合检测环境有机化合物的致突变性或潜在致癌性,如果同时用几种方法,则更有说服力.本文介绍了Ames试验、微量向前突变法和SOS显色试验,以及它们的应用实例.

Many procedues are available to test mutagenicity using microorganisms. Generally these methods are simple,rapid,sensitive and using small samples. They are suitable to test mutagenicity and potential corcinogenicity of environmental mutagens. If will be more then one method used for the same sample the result will be more convincible. This paper introduced Ames test. Micro-Forward-Mutaiton (MFM) and SOS chrome test, and listed some examples.