巢湖源水和饮用水的诱变性研究

Study on the Mutagenic Activity in Drinking Water from Chao Lake

采用组合致突变性试验对以巢湖水为水源的合肥市四水厂的水源水、沉淀池出水和出厂水有机浓集物的诱变性进行了研究。结果表明巢湖源水及其氯化饮用水，在细菌、真核细胞以至整体动物试验中都呈现一定诱变性。混凝沉淀工艺可除去部分诱变物。出厂水浓集物的致突变能力最强，其次为水源水，沉淀池出水最弱。多种方法联合应用，提高了饮水中诱变物检测的敏感性。研究还表明四种试验对饮水致突变性的检出敏感性顺序依次为ＳＣＥ＞微核（体内）＞枯草重组＞Ａｍｅｓ试验。结果提示饮水中致突变物部分来自水源水，但更主要系产生于氯化消毒过程中的卤代反应。作者强调防止巢湖污染，保护水源，降低水体富营养化程度和控制藻类繁殖，应引起有关方面的高度重视。

A battery of Short-term both in vitro and in vivo mutagenic test systems with different hereditary detecting endpoint were employed to study the possible genotoxicity of organic concentrates in raw, coagulation sedimented and finished water samples from The Hefei No. 4 Water Plant.Organic concentrates of raw and finished water had given uniformly positive results In all four bioassay systems.However, the mutagenic capabilities of the latter was obviously stronger than that of the former,The order of sensitivity for 4 tests to detect the mutagenicity of drinking water under the same dosoage of concentrates would be SCE>MN(in vivo)>Bacillus subtilis repair>Ames test.There were evidences for various types of mutagens in chlorinated drinking water.The genotoxic activity appears to originate primarily form halogenating reaction of chlorine with humic substances and water inhabiting algal presented in the raw water,because they have been considered as major precursors of mutagens,The essential strategies is going to protest water source from the contamination of industrial,agricultural and domestic waste-water,prevent rich nutritizated Water from intensifying,and control algal growth,