血清人绒毛膜促性腺激素放射免疫测定的临床应用

Clinical Application of Detection for Serum HCG by Radioimmunoassay

用RIA方法测定了未孕妇女50例、早孕75例,中孕62例、宫外孕69例、胎停育9例、葡萄胎105例、绒毛膜癌2例、睾丸胚胎癌4例之血清入绒毛膜促性腺激素(HCG)。其数值范围分别为24～33,32 596～61 263、14 873～25 562、1917～3 607、902～2916,119 231～505 359IU/L(95％可信限)、统计学分析结果除宫外孕与胎停育两组间没有显著差别外(p>0.05),其它各组均差别显著(p<0.01),同时还分析了绒毛膜癌、葡萄胎,睾丸胚胎癌治疗过程中血清HCG变化。由此可见血清HCG测定对上述例症的诊断、鉴别诊断和疗效观察有帮助。

Serum HCG was determined by RIA in 50 normal women, 75 early pregnancy, 62 middle pregnancy, 69 ectopic pregnancy, 9 dead fetal pregnancy, 15 hydatidiform mole, 2 chorioepithelioma and 4 embroy carcinoma of testis. The numerical values were 24~32, 32 569~61 263, 14 873~25 562, 1 917~ 3 607, 902~2 916, 119 234~505 359 IU/L (95% Fiducial limits) respectively. There was a great significance between each two groups statisticly(p<0.01) except between ectopic pregnacy and dead fetal pregnacy groups(p<0.05). The change of serum HCG was also analyzed druing treatment in chorioepithelioma, hydatidiform mole and embryoearcinoma of testis. The study indicates that serun HCG and sis could be useful for the diagnosis, differential diagnosis and assessment of therapeutic effect these diseases.