摘要
本研究通过联胺作用于体外培养的乳鼠心肌细胞，观察其激发和促进心肌细胞的脂质过氧化反应。结果发现随联胺浓度的增加，心肌细胞的形态学损伤逐渐加重，血栓素Ｂ２和脂质过氧化反应的最终产物丙二醛不断增加。联胺可用于制作心肌细胞脂质过氧化损伤模型。
Lipid peroxidation was initiated and facililtated in cultures eonatal rat myocardial cells with different concentrations of diamide for the first time.The cells showed contraction,some had peeled off,and lipid peroxides and thromboxane B2 in cells and medium increased with the icreasing of diamide concentration.These results suggested that myocardial cells are particularly sensitive to this treatment,and diamide may be used to make lipid peroxidation models in myocardial cells.
出处
《济宁医学院学报》
1994年第3期7-8,共2页
Journal of Jining Medical University
关键词
联胺
心肌细胞
过氧化脂质
Diamide
Myocardial cells
Lipid peroxidation
