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门脉高压性胃粘膜超微结构特征 被引量:5

ULTRASTRUCTURAL CHARACTERISTICS IN PORTAL HYPERTENSION GASTRICMUCOSA
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摘要 为进一步认识门脉高压性胃粘膜病变特点,利用透射电子显微镜对14例肝硬变食管静脉曲张病人及7名健康成人胃体上部胃粘膜进行了对比观察。发现门脉高压病人胃粘膜微静脉增多且管腔扩大;毛细血管内皮细胞肿胀导致管腔狭窄和基底膜增厚;粘膜下层动-静脉短路等特征。作者认为上述改变可能为肝硬变门静脉压力增高所致。 The alterations in mucosa of upper gastric body in 14 cases of liver cirrhosis with portalhypertension and 7 endoscopically normal subjects without chronic liver diseases were observed by trans-mission electron microscope. In liver cirrhosis with portal hypertension cases,venules in gastric mucosawere remarkably increased and dilated. Marked hypertrophy of capillary endothelium resulted in the re-duction of lumens. Basement membrane was thickened. Submucosal arteriovenous communications in-creased in number. We believe that they are caused by the gradual increase of portal venous pressure incirrhotic patients.
机构地区 北京军区总医院
出处 《解放军医学杂志》 CAS CSCD 北大核心 1994年第3期173-176,共4页 Medical Journal of Chinese People's Liberation Army
关键词 肝硬变 胃粘膜 超微结构 Liver cirrhosis Gastric mucosa Ultrastructure
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同被引文献12

  • 1穆毅,申耀宗,刘志发,韩斌,储一芳.门脉高压时胃粘膜病变发生机制的实验研究[J].中国病理生理杂志,1994,10(2):210-214. 被引量:6
  • 2许中伟,毓珊,林三仁,叶嗣懋,徐肇敏.肝硬化门脉高压与上消化道非曲张静脉破裂出血[J].中国实用内科杂志,1994,14(1):19-20. 被引量:50
  • 3[1]Smact HL.CliCical featuces,pathophysiology and yelevance ofportal hypertensive pastropathy.Endoecopy,1991,23:224.
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  • 5Smact HL.CliCical featuces,pathophyaloly ayd yelevance of portal hyoertensive pastropathy.Endoecopy,1991,23(4):224.
  • 6Viggiano TR.Portall hypertenslve intestinalvasculotathy:areview of the cllnlcal,endoscoplc,endoscopic,and histopathologic features.Am J Gastroenter,1992,87(8):944-954.
  • 73,SmartHL,TrigerDR.Clinicalfeatures,pathophysiologyandrelevanceofportalhypertensivegastropathy[J].Endoscopy,1991,23(4):224
  • 8杨海涛 周殿元.应用扫描电镜和透视电镜研究幽门弯曲菌的粘附、定居和致病性[J].中华消化杂志,1988,8:319-319.
  • 96,YoshidaN,GrangerDN,EvansDJ,etal.MechanismsinvolvedinHelicobacterpylori-inducedinflammation[J].Gastroenterology,1993,105:1431
  • 10郝志明,周春蜀.肝硬化并发的胃十二指肠病变与幽门螺杆菌[J].中国现代医学杂志,1999,9(8):30-31. 被引量:1

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