红景天中药复方提高高原机体劳动能力的效果观察

STUDY ON THE EFFECT OF THE COMPOUND OF RADIX ET RHIZOMA RHODIOLAE ON THE EXERCISE PERFORMANCE OF ORGANISMS AT SIMULATED HIGH ALTITUDE

为提高高原人体劳动能力，研制了以红景天提取物为主，含刺五加、黄芪和丹参的中药复方（９２０４０２复方）。在小白鼠减压缺氧（模拟海拔高度１００００ｍ）游泳实验中，９２０４０２复方组游泳时间明显长于对照组，分别为７５．８±４．４和６２．６±４．４ｍｉｎ，延长约２１．１％（Ｐ＜０．０５）；９２０４０２复方组游泳时间大于６０ｍｉｎ的存活率明显高于对照组，分别为５５．４和３６．９％（Ｐ＜０．０５）。在低压舱模拟海拔４５００ｍ进行的人体自行车功量计连续递增负荷运动试验中，９２０４０２复方组无氧阈明显高于对照组，分别为１．０８９±０．０７５和０．９０４±０．０７２Ｌ／ｍｉｎ（Ｏ＿２），提高约２０．５％（Ｐ＜０．０５）；运动心率明显低于对照组（Ｐ＜０．０５）；完成１５０Ｗ负荷运动的例数明显多于对照组（Ｐ＜０．０５）。结果表明，９２０４０２复方在提高高原机体劳动能力方面有明显作用。

n order to improve human work capacity at aItitude,the effects of acompound of Radix et Rhizoma Rhodiolae (920402 compound) on exercise per-formance of swimming-mice (survival time,ST) and men during hypoxiawere investigated. The mice were randomly divided into test(T)group(receiving 920402 compound) and control(C)group. The animals were for-ced to swim at a simulated altitude of 10000 m in a hypobaric chamber.Theresults showed that the ST in T and C groups were 75.8±4.4 min and 62.4±4.4 min respectively(P<0.05).The survival rate of T group at swimmingtime above 60 min was significantly higher than that of C group (P<0.05).The anaerobic threshold(AT_(GE))and exercise heart rate (HR) of humansubjects were determined while pedalling a bicycle ergometer with increasingload at a simulated altitude of 4500m.It was obversed that AT_(GE) in T andCgroups were 1.089±0.075 and 0.904 ± 0.072 l/min(O_2) respectively. Themean AT_(GE) value of T group was 20.5%more than that of C group (P<0.05).The HR of T group was significantly lower than that of C groupduring exercise at 150w(P<0.05).These data indicated that 920402 com-pound might play an important role in improving the physical performanceof organisms at high aItitude.