摘要
对10例成人胸腺微环境作超微结构观察.结果显示,根据胸腺上皮细胞超微结构形态和分布特征,可将其分为四种类型.Ⅰ型为包膜下-血管旁上皮细胞,分布于胸腺包膜下及皮筋交界区血管周围.Ⅱ型上皮主要要布于外皮质和整个胸腺实质,部分胞浆含分泌颗粒.Ⅲ型上皮分布于髓质,胞浆有形态多样的囊泡.Ⅳ型仅存在于髓质,数量极少.提示胸腺上皮细胞是异质性的,并且在胸腺内形成不同的局部微坏境.
The ultrastructural morphology of epithelial cells in ten human thymuses were identified. Four types of epithelial cells were distinguished: type 1 (subcapsular-perivascular): type Ⅱ (pale), present in the cortical and medullary zones: and type Ⅲ (dark) and type Ⅳ (large-medullary), present only in the medulla. These cells formed a network entrapping lymphocytes. In addition, some cells recombined themselves to form two types of associations that were found in the medulla: cystic cavities and Hassall's corpuscles. The various stages occurred in the course of intrathymic T-cell maturation at locations where a microenvironment vvas composed ofmorphologicallydistinctepithlial cells.
出处
《解剖学杂志》
CAS
CSCD
北大核心
1994年第3期248-251,共4页
Chinese Journal of Anatomy
关键词
胸腺
上皮细胞
异质性
超微结构
thymus
epithelia heterogeneous
ultrastructure
