从血浆与尿中儿茶酚胺和它的代谢产物含量说明推拿的镇痛作用

A STUDY OF THE ANALGESIC EFFECT OF MASSOTHERAYPY BY THE CHANGES IN THE CONTENT OF CATECHOLAMINE AND ITS METABOLITES IN PLASMA AND URINE

为了解推拿的镇痛作用与致痛物质的关系，分组进行了观察。第一组推拿前后９例急性软组织损伤病人血浆中儿茶酚胺（ＣＡ）的变化。第二组推拿前后３４例腰椎间盘突出症尿中儿茶酚胺（ＣＡ）和它的代谢产物含量变化。结果表明，推拿后血浆中ＮＡ含量下降非常显著，ＤＡ含量显著下降。推拿后尿中ＣＡ，ＤＡ，ＶＭＡ含量均明升高。说明体液中ＣＡ与推拿作用密切相关。ＣＡ含量在血浆中下降越显著，在尿中升高越显著，临床疗效越好。提示：在推拿过程中，体液内儿茶酚胺是参与调整镇痛的主要物质之一。

Observations have been made on two groups of patients to study the relationship between the analgesie effect of massotherapy andneurotransmitters of pain.One group consisting of 9 patients of acute soft tissue injury, were tested to deteromine their content of content of catecholamine (CA)in plas-ma before and after massotherapy. The other group consisting of 34 patients of lumbar intervertebral disc protrusion were tested to de-termine their content of CA and its metabolites before and after massotherapy.The results of both groups showed that after massotherapy content of noradrenaline(CA)and dopamine(DA)in plasma dropped dramatically while content of CA,DA and vanillymandelic acid (VMA)in urineincreased gratly. This sugged a closerelatonship be-tween CA content in body fluid and the effect of massotherapy. The gerater the decrease of CA in plasma and the increase of CA inurine, the better is the clinical therapeutic effect. It should be noted that during the massotherapy the CA content in body fluid is one of the essential substances that participates inurine, the better is the clinical therapeutic effect.It shold be noted that during the massotherapy the CA content in body fluid is one of the essntial substances that participates in reguation of pain-relieving.