青年人肺癌（42例临床分析）

Primary lung cancer in young patieuts(Clinical analysis of 42 cases)

军事医学科学院附属医院肿瘤科１９７８年６月至１９９３年９月住院治疗的青年人肺癌４２例，占同期住院肺癌病人的８．７％（４２／４８５）。男性３３例，女性９例，年龄２０－３９岁，中位年龄３５岁。误诊较为常见，本组为７６．２％，从首发症状到确诊平均３．１月。最常见的误诊疾病为肺结核和呼吸道感染。本组病理分类以小细胞肺癌最多（６１．９％），其次是腺癌和鳞状上皮癌。除３例病人进行手术外，其余３９例病人均以放疗和化疗为主进行综合治疗。治疗结果：中位生存期１３个月，１年生存率５０．８５％，２年生存率１８．４２％，３年生存率３．４２％。至今生存５例．

From June 1978 to September 1993, 485 lung cancer patients were treated in the department, amongthem 42 were under 40 years of age, accounting for 8.7%。 33 cases were male and 9 female。 The range of age was20 to 39. Lung cancer are frequently misdiagnosed in young patients. In this study, the misdiagnosis rate is 76.2%and the average misdiagnosis time is 3. 1 months. The most common misdiagnosis is tuberculosis, respiratory tractinfection etc。 Small cell lung cancer is the most common pathological type in this group, accounting 61.9%, theothers are adenocarcinoma and squamous cell carcinoma。 Only 3 patients were treated by surgical excision。Chemotherapy was the main modality of treatment in other 39 patients. The median survival time was 13 months。The survival rates in one, two and three years were 50.85%,18.42% and 3.43% respectively. As a result of thisstudy, the authors do not regard age as an important factor in prognosis, while the stage of the lesion, pathologicaltype and the operation possibility are more important. The key for a better result is early diagnosis。