122例肝病患者肝内HDV，HBV感染的研究

Study of Hepatitis D,BVirus Infections in Liverof l22 Patients with Hepatopathy

本文对１２２例各型肝病患者用ＡＢＣ法同时检测肝内ＨＤＶ及ＨＢＶ抗原。结果显示，ＨＢｓＡｇ和／或ＨＢｃＡｇ检出率为２７．８７％（３４例），其中ＨＢｃＡｇ为１３．２２％（１６例），ＨＢｓＡｇ为１８．１８％（２２例），两者无显著性差异（Ｐ＞０．０５）．ＨＤＡｇ检出率为４．９２％（６例），这６例丁型肝炎血中均检出ＨＢｓＡｇ和抗一ＨＢｃ，为慢性肝炎．在重肝、肝硬化和肝癌患者的肝内未检出ＨＤＡｇ．说明我国肝炎病毒感染仍以ＨＢＶ为主，ＨＤＶ感染率明显低于欧美，ＨＤＶ感染与ＨＢＶ感染关系密切，ＨＢＶ感染合并ＨＤＶ感染时易使病程慢性化。

ntigens of HBV and HDV were determined by ABC method in liver tissues of l22 pa-hents with various types of hepatopath.34 out of the l2l cases were HBsAg and / orHBcAg positive( 27. 87 %).The positive rates of HBsAg and HBcAg were l3.33% (16/121) and l8.18%(22 / l2l)respectively.Their difference was not statistically signi一ficant(P>0.05).A positive rate of HDAg was 4.97%(6/ l22).Among the 6 cases of hepatitis D。HBsAg and anti一HBc were detected in blood.The 6 cases were chronic hepatitis。HDAg was not detected in liver specimens of patients with severe hepatitis,hepatocirrhosis and hepatocellular carcinoma。The results above showed the infection of hepatitis virus was still main HBV in chinese。The infection rate of HDV in china was obviously lower than that in the countries in Europeand America,The relationship between HBV and HDV is close。For mixture infection of HBV and HDV,it turns to be chronic disease easily。