环状溴鎓盐免疫活性初探

The Preliminary Study of Cyclobromonium Salt on Immunological Competence in Vivo

实验小鼠腹腔注射环状溴鎓盐５ｍｇ／ｋｇ后，发现使脾抗体分泌细胞和循环抗体水平提高；腹腔巨噬细胞吞噬活性增强；外周血Ｔ淋巴细胞Ｅ－ＲＦＣ阳性率上升；并使被环磷酰胺损伤小鼠的免疫功能得以恢复。提示它具免疫增强活性。

The immunoehanoement of eyclobromonium salt was studied on normal mice and immunologic inhibited mice by cyclophosphamide. The contents of immune haemolysin and antibody secreting cells active of spleen, phagocytosis of peritoneal macrophage, and Erosette formation cells were improved significantly when mice were intraperitoneal injected cyclobromonium salt 5 mg/kg for 7￣8 d. Results indicated that the cyclobromonium salt had immunoenhance activity.