摘要
抗炎镇痛药布洛芬毒副作用较大,笔者以其为原料经酯化、肼解、酰化,合成了3种 布洛芬酰氨基-芳酰基硫脲衍生物,并经过元素分析和红外光谱鉴定。
Brufen is an effective drug for inflammation resistant and antipain. It has serious side effects. Using Brufen as the materials.the author has synthesized Brufenamid - aroyl - thiourea hy the reaction of esterifica-tion, hydrazinolysis andacylating. The structures of these new compounds have been appraised by means of the elemental analysis and infrared.
出处
《兰州医学院学报》
1994年第4期216-217,共2页
Journal of Lanzhou Medical College
关键词
布洛芬
酯化
肼解
酰化
合成
Bruf en
Esterif ication
Hydrazinolysis
Acylating