长期应用肝动脉栓塞治疗的肝细胞癌患者的影像分析

Imaging Analysis of HCC Cases with Long-term Hepatic Artery Embolism Therapy

本文对４２例ＨＣＣ患者的ＴＡＥ影像资料进行回顾性分析，发现供血动脉主干闭塞率６２％（２６／４２）。主要是由于以下几种因素引起的内皮细胞损伤所致：（１）导管和高压注射造影剂的物理刺激；（２）化疗药物的化学刺激；（３）导管嵌顿和长时间持续性注射化疗药物和栓塞剂所致的缺氧。因此，ＴＡＥ并非根治性、长久的治疗手段，应适时结合手术治疗，其手术切除的最佳时机是初次治疗后的３～５月。

We have reviewed trans-artery-embolism(TAE)imaging date in 42 hepatic cell cancer (HCC)cases,found 26 cases occured supply artery occlusion( 62%). This mainly caused by the folfowing factors which damage the endothelial cell:(1)Physical stimulus of catheter and injection of high-pressure contrast medium;(2) Chemical stimulus of chemotherapeutic agents;(3) Hypoxia caused by incarceration of catheter,long-term continuous injection of chemotherapeutic agents or embolic agents.So TAE is a non-radical,non-long-term therapy,which; hould combine with timely operation.The most opportune chance is 3～5 monthes after the first therapy.