摘要
通过在体兔坐骨神经-胫前肌标本,研究咪唑安定与维库溴铵之间可能的相互作用。在维库溴铵稳定状态神经肌肉阻滞下,咪唑安定0.3和1.5mg/kg分别抑制震颤强度23.5%和37%;而咪唑安定1.5mg/kg使维库溴铵累积剂量-反应曲线左移,但斜率不变。
study of the possible interactions between midazolam and vecuronium was performed in the rabbit in vivosciatic nerve-tibialis anterior muscule preparation。 Midazolam 0. 3 and 1. 5mg/kg caused 23.5%and 37%depres-sion of the twitch height respectively when a steady-state blockade of the twitch height had been induced by ve-curonium。 The buffer solvent of midazolam 1.5mg/kg did not change the steady-state blockade of vecuronium。Mi-dazolam l.5mg/kg caused left shift of the cumulative dose-response curve of vecuronium。
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1994年第5期247-249,共3页
Journal of Clinical Anesthesiology