小剂量哌替啶脊麻的临床观察

Clinical Observation of Low-dose Pethidine Spinal Anesthesia

１６０例成人下腹部及下肢手术，随机均分为对照组（布比卡因７．５ｍｇ）和哌替啶组（哌替啶５０ｍｇ＋麻黄碱３０ｍｇ，简称哌组）进行脊麻。与对照组相比，哌组麻醉起效时间明显延迟（Ｐ＜０．０５），而感觉和运动阻滞持续时间两组无差异（Ｐ＞０．０５），哌组术中应用辅助药例数明显少于对照组（Ｐ＜０，００１），且术后镇痛时间明显长于对照组（Ｐ＜０．００１）。两组病人麻醉后血液动力学变化及麻醉并发症和不良反应无差异（Ｐ＞０．０５）。哌组在获得较好的麻醉效果的同时，使病人术中镇静，消除术时的恐惧心理和牵拉反应，并能显著延长术后的镇痛时间。

60 cases of lower abdorninal(or lower limbs ) operations were performed under spinal anaesthesia,Theywere equally divided into pethidine group (pethidine 25rng+ephidrine 30mg,PG) and control group(bupivacaine7,5mg,CG).Results show that the onset interval of sensation and motor block in PG was distinctly longer thanthat in CG(P<0.05),but the duration of block was not significantly different(P>0.05).The number of patientsrequiring supplementary medication in PG was remarkablely less,however the duration of postoperative analgesiawas notablely longer as compared with that in CG,The circulatory changes and the incidence of complication weresimilar in two groups(P>0.05).