反流性食管炎几种诊断方法的研究

Study on Several Diagnostic Method in Reflux Esophagitis

本文对41例有典型反流性食管炎症状者,进行了内镜检查、粘膜活检、食管X线检查和核素闪烁显像综合检查.23例无反流症状者作对照.41例有反流症状组的内镜检查.均见食管粘膜有轻或中度炎症改变.病理活检的阳性率为76%,其中87%为中期食管炎.内镜检查用于观察有无食管炎症及其程度.41例均行核素闪烁显像检测,显示有反流者81%.本组病例中有31例行X线钡餐检查,显示有反流者53%.核素显像和X线钡餐用于确定有无胃食管反流,前者较后者敏感.

41 patients with symptomatic gastroesophageal reflux (GER) were studied with esophagoscopy, mucosal biopsy, barium esophagram, and scintigraphy. Additionally, 23 asymptomatic subjects were in control group. The endoscopy demonstrated that there were mild or moderate inflammation in 41 patients. The pathologic positive rate of esophageal biopsy was 76%. Endoscopy, esophageal biop-sy are two methods available to detect directly esophageal mucosal injury and degree of inflammation. Scintigraphy was performd in 41 patients, about 81% of the patients showed gastroesophageal reflux. The study of barium esophagram in 31 patients show 53% with reflux. The sensitivity of scintigraphy was higher than barium esophagram for diagnosis of gastroesophageal reflux. Above-mentioned examinations were nega-tive in control guoup.