口服美多心安治疗血管迷走性晕厥的疗效观察

A study on the effect of oral metoprolol for vasovagal syncope

２１例倾斜试验（ＴＴＴ）阳性的血管迷走性晕厥（ＶＳ）病人口服美多心安（５０ｍｇｂｉｄ）至少１周后复查ＴＴＴ。结果示４例因副作用停药，１７例复查ＴＴＴ有１２例转为阴性（７０．６％），１４例继续服用美多心安，平均随访５．９±６．５月，仅１例晕厥先兆复发，该例在第２次试验中为阳性。提示：口服美多心安可能是治疗ＶＳ的有效方法。

Abstract Twenty-one patients with unexplained syncope and positive response to tilt table test(TTT) were repeated TTT after administering metoprolol for more than one week.The results:Four cases discontinued metoprolol because of adverse effects.During the repeat tilt test,response was negative in 12 of 17 cases(70.59%).metoprolol was administered orally to 14 cases for an average of 5.9±6.5 months,only one patient who had positive response to the repeat TTT reoccured presyncope.These results indicate that administering metoprolol orally may be effective for vasovagal syncope.