水牛饲喂棉籽饼所致尿石症中矿物质代谢的研究

EFFECT OF DISTURBANCE OF MINERAL METABOLISM ON FORMATION OF URINARY CALCULI IN BUFFALO FED WITH HIGH CONCENTRATION COTTONSEED MEAL DIET

对中国某些棉区按传统方法用棉籽饼饲喂水牛所致尿石症中矿物质代谢失衡的情况进行了研究．棉籽饼采用煮沸或不煮沸、添加或不添加维生素Ａ和矿物质添加剂的三因子二水平的８种方法处理，分别饲喂８组（２４头）６～１１月龄未去势的公水牛犊，进行９０ｄ的饲养试验．结果表明，添加矿物质的１２头牛无一发生尿石症，不添加者有８头发病，棉籽饼煮沸和添加ＶＡ的效应不显著．结合血清和尿液中无机磷、钙和镁的动态变化分析，尿石组成的定性分析和发病牛的病理解剖学变化等结果，认为矿物质代谢失衡乃是牛饲喂棉籽饼所致尿石症的主要致病因子．

Twenty four male water buffalo calves aged 6 to 11 months, which were not castrated,were randomly alloted to eight groups and respectively fed with diet of 8 different combinations made up of cottonseed meal or boiled cottonseed meal, with or without mineral additive and vitamin A by the principle of three-way-layout design, and the feeding cxperiment lasted 90 days. The result showed that, there was no any case of urolithiasis in 12 experimental buffaloes fed with mineral additive, wherease 8 cases were induced in 12 buffaloes without feeding mineral additive. The factors of boiling cottonseed meal and adding vitamin A were not significant. According to the result of experimental induction of urolithiasis, the respective comparison of dynamic changes of calcium, phosphate and magnesium levels in serum and urine between the two groups of calves with and without mineral additive in their diet, the analysis of composition of urinary calculi in the experiment and pathological changes of induced cases of urolithiasis, it can be concluded that the mineral metabolic disturbance is the main pathogenetic factor in the formation of urinary calculi in buffalo fed with high concentration cottonseed meal diet.