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胎膜早破应用地塞米松是否诱发早产的观察 被引量:2

A CLINIC COMPARISON STUDY FOR DEXAMETHASONE WHETHER TO INDUCE PRETERM LABOR
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摘要 为探讨地塞米松促胎肺成熟是否同时诱发早产,对16例妊娠28~36周间胎膜早破孕妇用>10mg地塞米松促胎肺成熟者进行了回顾性比较研究。对照组选用同期16例可比性较好,未行促胎肺成熟处理的胎膜早破孕妇。结果用药组孕妇在用地塞米松处置后的24-48小时内,诸早产指标皆低于对照组(P>0.05).表明地塞米松促胎肺成熟不增加早产的危险性。 In order to know whether or not dexamethasone(DXM) simultaneously induces preterm labor when used for the acceleration of the fetal lung muturation(AFLM), a comparison study was carried out. The subjects were the 32 patients who suffered from preterm rupture of membrane(PROM) and were in the 28-36 gestational weeks. The results show that all of the three preterm labor targets of the study group(16 cases, administered with DXM for AFLM) were not significantly higher than those of the control group(16 cases, not given any medicine for AFLM)(P> 0.05), i.e., AFLM with DXM does not inerease the preterm labor risk.
作者 朱小明
出处 《南通医学院学报》 1994年第1期77-78,共2页 ACTA Academiae Medicinae Nantong
关键词 胎膜早破 地塞米松 早产 dexamethasone, preterm labor, acceleration of lung maturation, preterm rupture of membrane
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  • 2林海英.过期妊娠[J].医学理论与实际,1996,9:8-8.
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  • 5Robert S,Franklin W,Richard N.A comparision of thebioavailability of oral and intramuscular dexamethasone inwomenin late pregnancy. Obstetrics and Gynecology . 1997
  • 6Challis J R G.Mechanism of parturition and preterm labor. Obstetrical and Gynecological Survey . 2000
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  • 10Nadal,C.Dose-related opposite effects of hydrocortisone on hepatocyte proliferation in the rat. Liver . 1995

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