慢性胃炎患者幽门括约肌压力测定及其与辨证分型关系的研究

ENDOSCOPIC MANOMETRY OF PYLORUS SPHINCTER IN CHRONIC GASTRITIS WITH SYNDROME DIFFERENTIATION IN TCM

本研究采用内镜测压术，检测８０例证属脾胃虚弱型和肝胃不和型的慢性胃炎患者幽门括约肌压力变化。结果，脾胃虚弱型患者幽门括约肌收缩振幅降低、收缩频率减慢，而肝胃不和型患者幽门括约肌收缩振幅增高、收缩间期延长，与正常对照组比较均具非常显著意义（Ｐ＜０．０１）。表明幽门括约肌压力参数变化可作为慢性胃炎辨证分型的胃动力学参考指标，并可指导临床治疗用药和疗效评定。

The endoscopic manometry of pylorus sphincter and the syndrome differentiation in TCM were garried out among 80 chronic gastritis(CG) patients. Result: the peristaltic amplitude and frequency of the pylorus sphincter in 40 patients with of asthenia of the spleen and stomach(SASS) were lower and slower respectively than that of controls(P<0. 01).The basic pressure, peristaltic amplitude and duration of peristaltic wave in 40 patients with dominant liver-energy atttacking stomach(SDLAS) were higher and longer respectively than that of controls(p<0. 05, P<0. 01). The authers believe that these characteristic changes could be used as a reference of syndrome differentiation in CG and also a guide for how to apply materia medica and judge the curative effect. The endoscopic manometry of pylorus sphincter is an accurate, objective and convenient method in estimating the situation of gastric kinetics in CG.