摘要
作者用健康杂种狗18条,采用狗自身胆汁和胰蛋白酶混合液从胰管逆行注射的方法制做出“急性坏死性胰腺炎”的模型。随机分为两组:A组8条狗,仅给支持治疗;B组10条狗在支持治疗基础上给予腹腔灌洗。结果:支持治疗组8条狗平均仅存活26±3小时,存活率为0%;而灌先组10条狗中4条死亡(平均存活40±18小时),6条存活,存活率为60%。作者采用腹腔灌洗的方法治疗14例急性坏死性胰腺炎,有7例因病情恶化疑有感染或出现并发症而中转手术,其中4例治愈,3例死亡;另7例,6例完全治愈,1例死亡。作者认为腹腔灌洗适应于急性坏死性联腺炎的早期病例,即坏死尚未感感的病例。
Abstract Hybrid dogswereused inthis study. The model of acute necrotic duct injection of amixture of seyf-bila and trypsin. All the animals were randomly divided into two groups. Group A, 8 dogs with supporting therapy only,and Group B, 10 dogs with both supporting therapy and intraperitoneal perfusion. The results: Tge mean survival period of group A was 26±3hours Thesurvival rate was zero. Ingroup B 6out of 10 were survived and 4 dead (mean survival period 40±18 hour). 14 cases of acute necrotio pancreatitis received intraperitoneal perfusion trestment. 7 out of 14 casesunderwent operation because ofinfection or other complications, among them 4 were cured and 3 dead while in other 7 cases 6 were cured and ldead. The indication of this therapy was the early stage of the disease ie, no secondaryinfection cases.
出处
《普外临床》
CSCD
1994年第5期268-270,共3页