肝癌切除术中危险因素的逐步回归分析

The regression analysis of risk factors of hepatectomies in liver cancer patients

我们应用逐步回归分析法对我院经手术及病理确诊的８４例原发性肝癌进行了统计分析。结果表明在调查的１３个因素中（包括肿瘤位置、直径、有无肝硬变、肿瘤与周围器官有无粘连、麻醉方法、手术切口类型、肝切除量、切线距瘤体距离、肝血流阻断方式、出血量、补血量、手术时间及术中低血压时间），术中出血量及手术时间与术后恢复的关系最大。如出血量＞１５００ｍｌ，手术时间＞２４０ｍｉｎ则术后并发证明显增加。其它因素则多数与这两项因素存在不同程度的相关关系。术中注意控制这些因素有助于缩小术后风险。

Abstract In this study, regression analysis of operative risk factors was made on the basis of 84 hepatectomies performed on primary liver cancer patients. Among 13 possible operative risk factors were the size and location of the tumor, concomitant liver cirrhosis, tumor invasion of adjacent organs, anaesthesia used, incision, the amount of liver parenchyma removed, hepatic blood flow blockade, operative blood loss, and operating time. Blood loss and operating time were found to be positively correlated to the postoperative complications with the rate of complications greatly increased upon the operating time longer than 240 minutes and the blood loss more than 1500ml, while the other factors being more or less correlated with,he two major factors. Hence comprehensive control of all risk factors would aid in decreasing mortality and morbidity.