摘要
应用人白细胞干扰素(HuIFN-α)联合板蓝根注射液(IRI)方案离体处理16例乙型肝炎病人外周血淋巴细胞,观察病人SCE平均频率的动力学变化。结果表明,HuIFN-α联合IRI处理实验组SCE平均频率明显低于对照组,差异高度显著(P<0.01)。急性与慢性乙型肝炎实验组SCE平均频率分别低于各自的对照组,差异也高度显著(P<0.01);两者之间SCE平均频率差异不显著(P>0.05)。
In vitro treatment of hepa-titis B virus-infected peripheral lymphocytes from 16 hepatitis B patients with human interferon-α(HuIFN-α)combined with injectio radicis isatis(IRI),induced a decrease in the frequency of sister-chromatid exchanges(SCE),showing a significant difference(in mean SCE frequency)from the control group.There were also significant differences between patients with acute or chronic hepatitis treated with HuIFN-α combined with IRI and their respective control groups.But no difference was found between the acute and chronic hepatitis B patients treated with HuIFN-α combined with IRI.
出处
《青岛医学院学报》
1994年第2期87-90,共4页
Acta Academiae Medicinae Qingdao Universitatis
关键词
干扰素
板蓝根
乙型肝炎
DSCE
淋巴细胞
human interferon type I
radicis isatis
hepatitis B
sister chromatid exchange