摘要
应用ＥＬＩＳＡ检测了正常人和肺结核患者的血清可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）和抗ＰＰＤ抗体水平。结果表明，活动性肺结核患者的血清ｓＩＬ－２Ｒ和抗ＰＰＤ抗体呈正相关（γ＝０．４３３，Ｐ＜０．００１），而且两者的水平明显高于正常对照组；抗ＰＰＤ抗体阳性的活动性肺结核患者血清中ｓＩＬ－２Ｒ浓度明显高于抗体阴性患者，提示血清ｓＩＬ－２Ｒ浓度测定可以反映肺结核患者细胞免疫功能状态。
Serum Soluble interleukin 2 receptor (sIL-2R) and anti-PPD IgG levels were measured in patients with active pulmonary tuberculosis by ELISA. The concentrations of serum sIL2R and anti-PPD IgG in patients with active pulmonary tuberculosis were higher than those of normal controls. There was a positive correlation between the concentration of sIL-2R and the anti-PPD IgG level. The concentrations of sIL-2R in patients with positive anti-PPD IgG were significantly higher than in those with negative one. The results suggested the measurements of sIL-2R levels may serve as a parameter fo reflecting the decreased cellular immunity in patients with active pulmonary tuberculosis.
出处
《上海免疫学杂志》
CSCD
北大核心
1994年第6期343-345,共3页
Shanghai Journal of Immunology
