摘要
105例Graves病(GD)于治疗前及治疗后5年分别进行甲状腺细针抽吸细胞涂片(FNA),甲状腺功能,抗TMA、抗TGA检查,结果:(一)第1次FNA,75例为GD,30例桥本氏甲状腺炎(HT);第2次FNA,75例GD中,10例转为HT,血抗TMA及/或抗TGA均较初次升高;30例HT中,5例转为GD,血抗TMA及/或抗TGA均较初次下降。(二)5年随访,共10例GD自发进入甲减或亚临床甲减,其中1例又由甲减回复到正常。作者认为FNA、自身抗体及甲状腺功能相关,GD与HT可以互相转变。
five-year follow-up study was done on 105 cases of Graves’ hyperthyroidismbefore and after receiving antithyroid drugs.All cases were examined with fine needleaspiration(FNA)of biopsy.Serum TT3,TT4.TSH,anti-TMA and anti-TGA weredetermined.It showed that(1)Among the 105 cases,75 cases were diannosed as Gra-ves’disease(GD), and 3 0 cases as Hashimoto’s disease(HT)by the first FNA study;10 of the 75 GD cases evolved to be HT with increased titers of anti-TMA and /oranti-TGA,5 of the 30 HT cases turned out to be GD with decreased titers of anti-TMAand/or anti-TGA by the second FNA,(1) In five-year follow-up study of 105 cases,there were 10 cases that spontaneously developed hypothyroidism or subclinical hypothy-roidism. One of them had clinical recovery with normal thyroid function,These datasuggested that FNA,autoantibodies and thyroid functions are interrelated. GD and HTare interconvertible.
出处
《上海医学》
CAS
CSCD
北大核心
1994年第6期323-325,共3页
Shanghai Medical Journal
关键词
桥本病
甲状腺炎
甲状腺球蛋白
Graves’disease (GD),Hashimoto’s thyroiditis(HT)
Anti-thyroid microsomal antibody(TMA)
Anti-thyroglobulin antibody(TGA)