摘要
在ＳＤ大鼠静脉内注入不同剂量的ＡｕｇⅡ后大鼠的饮盐水量明显增加。切除肾上腺的大鼠也出现强烈的饮盐水行为，但给予适当量的难固酮可消除这种行为。脑室内注入巯甲丙脯酸可阻断静脉内给与ＡｎｇⅡ所引起的大鼠的饮盐水行为。本文对ＡｎｇⅡ的作用机理进行了探讨。
Intravenous infusion of varinus doses of Aug Ⅱ caused significant increases ofthe salt intake in S-D rats as a result of natriuretic action of the drug.The phenomenon could be abolished by administration of aldosterone but unaffected by adrenalectomy.Captoptil could suppress the Ang Ⅱ effect.Discrepancies with a previous work on the interpretation of the action mode of Aug Ⅱwere discusseed.
出处
《生理学报》
CAS
CSCD
北大核心
1994年第2期187-192,共6页
Acta Physiologica Sinica
关键词
血管紧张不Ⅱ
静脉灌流
饮盐
Aug Ⅱ
intravenous infusion
captopril
sodium intake
