α-溴代肉桂醛及烷烯基酸酯类对微生物的呼吸代谢的抑制作用研究

Inhibition of the Respiration of Microorganism byα-Bromo Cinnamaldehyde and Alkenoic Acid Esters

采用氧电极法对细菌、霉菌，酵母菌的呼吸耗氧量进行测定，探讨α－溴代肉桂醛及烷烯基酸酯类的抑菌机理。结果表明α－溴代肉桂醛及烷烯基酸酯类能有效地抑制微生物的呼吸代谢途径。比较了典型抑制剂对防腐剂的叠加率，得出α－溴代肉桂醛，α－溴代肉桂酸甲酯，富马酸甲酯，溴代富马酸二甲酯均主要抑制呼吸代谢途径中的ＴＣＡ循环，其中，溴代富马酸二甲酯对ＥＭＰ途径也有明显的抑制作用。

he antimicrobial activities of α-bromo cinnamaldehyde and alkenoic acid esters against Eschericheae coli, Bacillus megatherium, Aspergillas niger, Saccaromyces cererisiae were determined with oxygen electrode in culture medium. An excellent effect was observed that fungi and bacterium were inhibited by α-bromo cinnamaldehyde and alkenoic acid esters. The different combinations between α-bromo cinnamaldehyde and alkenoic acid esters significantly increase the inhibition rare to microorganisms.The results of respiration experiment show that α-bromo cinnamaldehyde and alkenoic acid esters inhibit the tricarboxylic acid cycle. It was so that α-bromo cinnamaldehyde and alkenoic acid esters inhibit some respiratory enzymes activities.