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细胞角蛋白在硬腭粘膜良恶性病变中的表现及意义 被引量:3

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摘要 选用抗细胞角蛋白单抗LP34、LL001和LL025分别对硬腭部正常粘膜上皮、乳头状瘤和鳞癌进行了免疫组化观察.结果显示,LP34及LL001在正常粘膜及乳头状瘤上皮细胞中的表现基本相似,阳性部位主要在棘层和颗粒层;而LL025在乳头状瘤中的表现则比正常粘膜为强烈.对于鳞癌的观察结果显示,鳞癌对于细胞角蛋白的表达均有缺失现象,尤其是分化差的病变.结果表明LP34是一种较有效的可用于判断病变恶性程度的抗体,此外可用于进行上皮来源的病变的鉴别诊断,LL025及LL001则可用于判断上皮的类型及显示上皮细胞的更新代谢和分化情况.
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 1994年第2期107-108,153,共3页 Journal of Practical Stomatology
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