流行性出血热患者β_2-微球蛋白的检测与分析

DETECTION AND ANALYSIS OF β_2 - MICROGLOBULIN IN PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER

本文对276例流行性出血热患者进行了血清β_2-MG检测。其结果表明,血清β_2-MG含量在各临床类型之间有显著性差异(P<0.01),随临床类型的加重显示增高趋势。血清β_2-MG含量在不同病期之间也有显著性差异(P<0.01),即发热期开始增高,少尿期达高峰。血清β_2-MG检测结果能反映流行性出血热肾功能损害的程度,可作为诊断流行性出血热的辅助指标。

The detection of serum B2 - MG was carried out in 276 patients with epidemic hemorrhagic fever. The results showed that P2 - MG was significantly different in different clinical types of the disease (P<0. 01). B2 - MG showed increasing trend when the clinical types became more serious. It also showed obvious differences during different courses of the disease (P<0. 01). It was higher at time of fever, and highest at oliguric stage. The results of serum B2 -MG can reflect the degree of the kidney damage caused by epidemic hemorrhagic fever and it can be used as an auxiliary index for the diagnosis of epidemic hemorrhagic fever.