病毒性肝炎患者检测血清肝脏特异性膜脂蛋白(LSP)的意义

The Significance of Serum LSP Determination in Viral Hepatitis

本文检测94例各型病毒性肝炎患者血清肝脏特异性膜脂蛋白(LSP)的阳性率及水平,二者的高低顺序均为 AH>CAH>CPH。急性肝炎中 LSP 阳性组的 SGPT 水平显著高于LSP 阴性组。随访3例急性肝炎的血清 LSP 均在发病3周内转阴。检测抗-LSP 和 LSP 同时阳性频率为:CAH(72.72%)>AH(58.33%)>CPH(11.76%)提示二者均可作为肝损害指标、病情预测及判断预后的指标。

Serum LSP was determined in 94 cases of various types of viral hepatitis.Thepositivity and titer of serum LSP indicated that AH>CAH>CPH.In acute hepatitis,the level of SGPT of the positive LSP group was higher than that of the negativeLSP/group.The follow-up study of three cases with acute hepatitis was carriedout.The result showed that all cases had seroconversion from positive to negativefor LSP.Serum anti-LSP and LSP were determined simultaneously,the positivityof both indicated that CAH (72.72%)>AH (58.33%)>CPH (11.76%).This suggestedthat serum LSP and anti-LSP appeared to be the most useful markers of hepaticdamage and prognostic indicators.